Anaerobic digestion (AD) is viewed as an attractive method for waste stabilization prior tolandfills as pre-treatment to reduce significant pollution load to the environment Optimizinganaerobic digestion process aims to maximize organic waste conversion to biogas at shortdigestion period, The optimization of high solid concentration of MSW in a laboratory scalereactor was carried out to know the maximum biogas production yield,This paper presents the findings of the study on high solid AD process in single whichinvolves enhanced pre-stage (hydrolysis and acidification) and methane phase,