功能(生物学)
计算生物学
蛋白质结构
国家(计算机科学)
计算机科学
认知科学
生物
进化生物学
心理学
生物化学
算法
标识
DOI:10.1016/s0968-0004(02)02169-2
摘要
The recent suggestion that the classical structure-function paradigm should be extended to proteins and protein domains whose native and functional state is intrinsically unstructured has received a great deal of support. There is ample evidence that the unstructured state, common to all living organisms, is essential for basic cellular functions; thus it deserves to be recognized as a separate functional and structural category within the protein kingdom. In this review, recent findings are surveyed to illustrate that this novel but rapidly advancing field has reached a point where these proteins can be comprehensively classified on the basis of structure and function.
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