新皮层
神经科学
层流
皮质(解剖学)
大脑皮层
血流
计算机科学
生物
医学
心脏病学
物理
热力学
作者
Franca Schmid,Matthew Barrett,Patrick Jenny,Bruno Weber
出处
期刊:NeuroImage
[Elsevier]
日期:2019-08-01
卷期号:197: 792-805
被引量:87
标识
DOI:10.1016/j.neuroimage.2017.06.046
摘要
An amazingly wide range of complex behavior emerges from the cerebral cortex. Much of the information processing that leads to these behaviors is performed in neocortical circuits that span throughout the six layers of the cortex. Maintaining this circuit activity requires substantial quantities of oxygen and energy substrates, which are delivered by the complex yet well-organized and tightly-regulated vascular system. In this review, we provide a detailed characterization of the most relevant anatomical and functional features of the cortical vasculature. This includes a compilation of the available data on laminar variation of vascular density and the topological aspects of the microvascular system. We also review the spatio-temporal dynamics of cortical blood flow regulation and oxygenation, many aspects of which remain poorly understood. Finally, we discuss some of the important implications of vascular density, distribution, oxygenation and blood flow regulation for (laminar) fMRI.
科研通智能强力驱动
Strongly Powered by AbleSci AI