Poster

The authors would like to present a case of a 30-year old female patient with the symptoms of acrocyanosis together with nail changes (leukonychia, onycholysis), who has been treated with valproic acid for 3 years.Acrocyanosis is a painless condition, characterized by symmetrical discoloration of various shades of blue colour, involvimg hands, feet and face, often associated with hyperhidrosis of hands and feet and exacerbated by cold.Due to multifactorial aetiology of the phenomenon, this case may be considered as a diagnostic challenge.Valproic acid has been described as a causative factor of various skin and nail conditions, also onycholysis.On the other hand, nail abnormalities have been observed in patients with acrosyndromes (for example erythromelalgia).Capillaroscopy together with photoplethysmography revealed numerous abnormalities.The patient remains under the observation and monitoring of any possible signs and symptoms of connective tissue diseases. P002Vesicular contact reaction, progressing towards erythema multiforme of a dermal type in a 27-year old patient after cesarean section Czarnecka-Operacz, M.;