化学
硝基
氯
亲核芳香族取代
亲核取代
氟
亲核细胞
取代反应
自由基亲核芳香族取代
药物化学
群(周期表)
替代(逻辑)
有机化学
氯原子
催化作用
烷基
计算机科学
程序设计语言
标识
DOI:10.1070/rc2003v072n08abeh000809
摘要
The published data on the comparative activities of the nitro group, fluorine and chlorine in aromatic nucleophilic substitution reactions are generalised and systematised. The factors influencing the relative activities of these substituents, viz., the structure of the substrate, the nature of the nucleophile and reaction conditions, are discussed. The synthetic applications and possible mechanisms of nucleophilic substitution of the nitro group, fluorine and chlorine in aromatic compounds are considered. The bibliography includes 265 references.
科研通智能强力驱动
Strongly Powered by AbleSci AI