材料科学
凝血酶
血小板
丝氨酸蛋白酶
血小板活化
聚合物
蛋白酶
生物物理学
生物化学
酶
免疫学
化学
医学
生物
复合材料
作者
Sylvia T. Gunawan,Kristian Kempe,Thomas Bonnard,Jiwei Cui,Karen Alt,Lok Soon Law,Xiaowei Wang,Erik Westein,Georgina K. Such,Karlheinz Peter,Christoph E. Hagemeyer,Frank Caruso
标识
DOI：10.1002/adma.201502243
摘要
Smart poly(2-oxazoline) (POx)-based multifunctional polymer capsules that specifically target glycoprotein (GP) IIb/IIIa on the surface of activated platelets are degraded by the serine protease thrombin and release the urokinase plasminogen activator loaded into the polymer capsules, only in the area of acute thrombosis.
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