医学
聚己二酮
支架
外科
可生物降解聚合物
内窥镜支架置入术
胃肠道
耐火材料(行星科学)
内科学
聚合物
天体生物学
物理
有机化学
化学
作者
Stanislav Rejchrt,Marcela Kopáčová,Jan Brožík,Jan Bureš
出处
期刊:Endoscopy
[Georg Thieme Verlag KG]
日期:2011-05-27
卷期号:43 (10): 911-917
被引量:100
标识
DOI:10.1055/s-0030-1256405
摘要
Biodegradable stents, which are made of various synthetic polymers, such as polylactide or polyglycolide, or co-polymers, such as polydioxanone, can be used for the treatment of benign refractory stenoses of the gastrointestinal tract. Here we report 11 patients (median age 41) with stenosing Crohn’s disease of the small and/or large intestine. Endoscopic insertion of a biodegradable stent was successful at the first attempt in all patients except one. Subsequent follow-up was for a mean of 16 months, median 17 months, range 12 – 29 months. Early stent migration (between 2 days and 8 weeks) was seen in three patients. Mucosal overgrowth (epithelial hyperplasia) was not observed in any of the patients during the follow-up period. The high rate of early stent migration might be solved by appropriate tailoring and further improvements in the design of the biodegradable stents. Proof of long-term efficacy and safety requires further studies.
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