Obesity is an independent risk factor of cardiovascular disease(CVD).Obesity is closely related with hypertension,elevated levels of blood lipid and diabetes,and is responsible for the increment of heart disease occurrence rate.But the mortality rate in obesity patients with heart disease is lower than that in the patients whose weight is normal or lower.This kind of phenomenon is called as obesity paradox.Further researches on mechanisms of obesity paradox will bring a kind of new way for the treatment of CVD.