Objective To observe the curative effect on acne rosacea treated with Meilu acne removing and metroniolazole. Methods The treatment group was treated with Meilu acne removing and metryl 2/d for 4~8 weeks and control group was treated with Benzoyl peroxide. Results There was significant difference between two groups P0.01 at end of 4 week and 8 week(χ2=6.96,P0.01)(χ2=6.35,P0.01). Conclusion This method might be a good choice to treat acne rosacea that better than Benzoyl peroxide paste.