Mikania micrantha is a perennial weed of Asteraceae originated from South America and Center America. It has invaded to Southeast Asia, Pacific region and South China. Because Mikania micrantha grows very fast and is hard to control, it has become one of the worlds worst weeds. In this paper,the history and status of the study on Mikania micrantha was reviewed. The research on Mikania micrantha mainly focused on biology, ecology, harm and control. Although it has gotten some progress about Mikania micrantha research, it is a tough task to solve Mikania micrantha problem.