Experimental study on the therapeutic of garlic aqueous extract in mice diarrhea

Objective To study the therapeutic effect of Garlic aqueous extract on the diarrhea.Methods By intraperitoneal injection 0.3ml/10g of E.coli to produce diarrhea mice model,then intragastric administrating mice normal saline,garlic aqueous extract,positive control drugs to observe the general state and behavior of mice and record the number of stools,loose stools,by calculating diarrhea rate,loose stools rate,diarrhea index to study therapeutic action of Garlic aqueous extract on diarrhea.Results Garlic aqueous extract can decrease the number of diarrhea,transform loose stool to drying stool,and improve their mental state,Compared with modle group,high and mid-dose group of Garlic aqueous extract,diarrhea index were significantly lower than that the model group(P﹤0.05).Conclusion Garlic aqueous extract can decrease the number of diarrhea and diarrhea index,have the therapeutic effect on diarrhea.