Study on synthesis of fungicides diethofencarb

Diethofencarb was synthesized from 1,2-diethoxybenzene by nitrification,reduction and condensation reaction.The optimum synthetic conditions:reaction temperature is 90 ℃,amount of catalyst is 3%,reaction pressure is 1.5 MPa and reaction time is 3 h.The optimum reaction conditions in condensation reaction were also obtained:with triethylamine as acid binding agent,molar ratio of toluene to reactant is 2.1 ∶1,molar ratio of 3,4-diethoxy-aniline to isopropyl chloroformate is 1 ∶1.3 and reaction time is 0.5 h.The total yield of diethofencarb is above 80.38%,its purity is above 98%.