Chemical constituents from Ficus pumila

Objective To investigate the chemical constituents from Ficus pumila and to provide the material basis for quality control.Methods The chemical constituents were separated and purified by silica gel,Sephadex LH-20,ODS,and preparative HPLC column chromatographies.Their structures were determined by physicochemical properties and spectral data analyses.Results From 95% ethanol extract of F.pumila,21 compounds were isolated and identified as rutin(1),kaempferol 3-O-α-L-rhamnopyranosyl(1→6)-β-D-glucopyranoside(2),isoquercitrin(3),quercitrin(4),dihydrokaempferol 5-O-β-D-glucopyranoside(5),dihydro-kaempferol 7-O-β-D-glucopyranoside(6),maesopsin 6-O-β-D-glucopyranoside(7),secoisolariciresinol 9-O-β-D-glucopyranoside(8),chlorogenic acid(9),protocatechuic acid(10),caffeic acid(11),5-O-caffeoyl quinic acid methyl ester(12),p-hytroxybenzoic acid(13),vanillic acid(14),5-O-caffeoyl quinic acid butyl ester(15),β-amyrin acetate(16),daucosterol(17),phaseic acid(18),vomifoliol(19),(1′S,6′R)-8′-hydroxyabscisic acid β-D-glucoside(20),and 1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid(21).Conclusion Compounds 5—15,18,20,and 21 are isolated from this plant for the first time,and compound 5—8,12,15,20,and 21 are found in plants of Ficus Linn.for the first time.