Clinical efficacy of combined Chinese and Western medicine in treatment of Alzheimer disease: a meta-analysis

Objective To compare the effect of combined Chinese and Western medicine versus single therapy in treatment of Alzheimer's disease. Methods By searching CNKI,Wanfang,VIP databases,the randomized controlled trials( RCTs) about Alzheimer disease were included. The quality of the articles was assessed. The data was input and analyzed by RevMan5. 0 software. Results Fifteen randomized controlled trials( RCTs) met the inclusion criteria,including 13 RCTs( 973 patients) with Western medicine as control group,and 2 RCTs( 87 patients) with Chinese herb as control group. Meta analysis showed that the efficacy of combined Chinese and Western medicine was better than that of Chinese herb or Western medicine alone. Conclusion The curative effect of combined Chinese and Western medicine in treatment of Alzheimer's disease is better than that of single therapy.