医学
内科学
胃肠病学
急性胆囊炎
胆囊炎
C反应蛋白
胆囊切除术
前瞻性队列研究
回顾性队列研究
作者
José Ángel Diez Ares,Rosario Martínez García,Nuria Estellés Vidagany,Nuria Peris Tomás,Manuel Planells Roig,Marta Valenzuela Gras,Tomás Ripollés González
标识
DOI:10.17235/reed.2020.7282/2020
摘要
The diagnosis of gangrenous acute cholecystitis represents a diagnostic challenge for the physician and is rarely identified preoperatively. We report a longitudinal prospective study in 180 patients who underwent cholecystectomy for acute cholecystitis. A ROC curve was obtained to determine the preoperative cut-off for various biomarkers (neutrophil to lymphocyte ratio [NLR], C-reactive protein [CRP], platelet to lymphocyte ratio [PLR], lactate and procalcitonin) and their association with both preoperative and postoperative findings. The area under the curve (AUC) for NLR, CRP, PLR, lactate and procalcitonin was 0.75, 0.8, 0.65 and 0.6, respectively. NLR > 5 and CRP > 100 are still independent factors for gangrene (adjusted odds ratio [OR], 2 and 2.1, respectively).
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