Effects of dietary α-lipoic acid on the growth and antioxidative responses of juvenile abalone Haliotis discus hannai Ino

Aquaculture ResearchVolume 41, Issue 11 p. e781-e787 Effects of dietary α-lipoic acid on the growth and antioxidative responses of juvenile abalone Haliotis discus hannai Ino Wenbing Zhang, Wenbing Zhang Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao, ChinaSearch for more papers by this authorQiyong Chen, Qiyong Chen Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao, ChinaSearch for more papers by this authorKangsen Mai, Kangsen Mai Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao, ChinaSearch for more papers by this authorWei Xu, Wei Xu Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao, ChinaSearch for more papers by this authorXiaojie Wang, Xiaojie Wang Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao, ChinaSearch for more papers by this authorZhiguo Liufu, Zhiguo Liufu Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao, ChinaSearch for more papers by this author Wenbing Zhang, Wenbing Zhang Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao, ChinaSearch for more papers by this authorQiyong Chen, Qiyong Chen Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao, ChinaSearch for more papers by this authorKangsen Mai, Kangsen Mai Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao, ChinaSearch for more papers by this authorWei Xu, Wei Xu Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao, ChinaSearch for more papers by this authorXiaojie Wang, Xiaojie Wang Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao, ChinaSearch for more papers by this authorZhiguo Liufu, Zhiguo Liufu Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao, ChinaSearch for more papers by this author First published: 13 August 2010 https://doi.org/10.1111/j.1365-2109.2010.02592.xCitations: 45 Correspondence: W Zhang, Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao 266003, China. E-mail: [email protected] Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract A feeding experiment was conducted to determine the effects of α-lipoic acid (LA) on the growth and antioxidative responses of juvenile abalone Haliotis discus hannai Ino. Six purified diets supplemented with 0, 200, 400, 800, 1600 and 3200 mg kg−1 of LA, respectively, were fed to abalone for 16 weeks in a flow-through water system. The results showed that the weight gain ratio (WGR) increased with the dietary LA levels, and reached the highest value in the group with 800 mg kg−1 dietary LA supplement. Glutathione peroxidase activity in the 800 mg kg−1 dietary LA group was significantly higher than that in the dietary LA-deficient (0 mg kg−1) group. Superoxide dismutase activities in the 200, 400 and 800 mg kg−1 groups were significantly increased. Supplements of 200, 400 and 800 mg kg−1 dietary LA elevated the total antioxidative capacity significantly. The glutathione level in the hepatopancreas increased significantly with the dietary LA supplements in a dose-dependent manner (except for the 200 mg kg−1 group). Catalase and malondialdehyde in the hepatopancreas were not significantly affected by dietary LA. In conclusion, dietary LA promoted the growth and stimulated the antioxidative defence capacity of abalone. Based on the data of WGR, the optimal dietary LA supplement for juvenile abalone was found to be 709 mg kg−1 using piece-wise linear analysis. Citing Literature Volume41, Issue11October 2010Pages e781-e787 RelatedInformation