乙酰胆碱酯酶
化学
香兰素
化学成分
立体化学
光谱分析
有机化学
酶
色谱法
光谱学
物理
量子力学
作者
MI Cheng-neng,Mei Wen-li,Zuo Wen-jian,Cai-Hong Cai,Hao Wang,Shaopeng Li,Hao‐Fu Dai
标识
DOI:10.16333/j.1001-6880.2015.04.002
摘要
Fourteen compounds were isolated from the branches of Amoora tetrapetala and structurally identified by spectral analysis. The compounds were identified as 22ξ-hydroxytirucalla-7,24-dien-3,23-dione(1),dymacrin D(2),zeorin(3),α-spinasterol(4),8-hydroxy-6-methoxy-3-pentylisocoumarin(5),lichenxanthone(6),10-oxo-isodauc-3-en-15-al(7),(+)-ent-ficusol(8),3-methoxy-4-hydroxybenzoate(9),vanillin(10),methyl 2,4-hydroxy-3,6-dimethylbenzoate(11),methyl 2-hydroxy-4-methoxy-6-propylbenzoate(12),methyl 2,4-dihydroxy-6-methylbenzoate(13) and methyl hydrogen succinate(14). All the compounds were isolated from this genus for the first time. All chemical constituents were tested for acetylcholinesterase inhibitory activity using the Ellman colorinetric method. The results indicated that compound 11 exhibited inhibitory activity against acetylcholinesterase.
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