立体中心
对映选择合成
化学
四级碳
表面改性
胺气处理
吡唑酮类
有机催化
有机化学
组合化学
催化作用
物理化学
作者
Shizhou Liu,Mengchao Tong,Yang Yu,Hexin Xie,Hao Li,Wei Wang
出处
期刊:ChemInform
[Wiley]
日期:2015-11-12
标识
DOI:10.1002/chin.201548140
摘要
A chiral amine catalyzed enantioselective α-functionalization of α-substituted β-ketocarbonyls with electron-deficient vinylarenes has been developed to construct the dicarbonyl products with the formation of a chiral all-carbon quaternary stereocenter. The products can be used for the efficient synthesis of useful but challenging chiral quaternary centered pyrazolones.
科研通智能强力驱动
Strongly Powered by AbleSci AI