Bile Acids Modulate T-cell Response and Function in Liver Cancer
出处
期刊：Cancer Discovery [American Association for Cancer Research] 日期：2025-01-01
标识
DOI：10.1158/2159-8290.cd-rw2025-007
摘要
Major Finding: Elevated bile acids (BA) in liver cancer contribute to T-cell dysfunction.Concept: BA accumulation in T cells promotes ER stress, reducing effector function and viability. Impact: Modulating BA synthesis or intake may improve immunotherapy response in liver cancer.
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(2025-6-4)
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