Palladium-Catalyzed Dual C–H Arylation/Cyclization Reaction of Iodoferrocenes with ortho -Bromobenzamides for the Construction of Arylated Isoquinolone-Fused Ferrocenes

We reported a palladium/norbornene-catalyzed dual intermolecular C–H arylation/intramolecular cyclization reaction of iodoferrocenes with ortho -bromobenzamides, enabling the formation of arylated isoquinolone-fused ferrocenes in a straightforward and effective manner. This method has a broad substrate scope and good functional group compatibility, while the gram-scale reaction demonstrates the practicality of this method.