多酚
一氧化氮
TLR4型
炎症
柚皮素
活性氧
脂多糖
化学
磷酸化
染料木素
黄酮类
药理学
细胞凋亡
类黄酮
细胞内
信号转导
巨噬细胞
受体
橙皮苷
对接(动物)
肿瘤坏死因子α
生物化学
作者
Abel Wend‐Soo Zongo,Kaili Gao,Silvère D. Zaongo,Daniel Zogona,Duoxia Xu,Ningxiang Yu,Xianghe Meng
出处
期刊:Food & Function
[Royal Society of Chemistry]
日期:2025-01-01
卷期号:16 (20): 8077-8094
被引量:2
摘要
) with TLR4 and NF-κBp65 proteins, primarily through hydrogen bonding, π-stacking interactions, and van der Waals forces. These results suggest that these compounds play a central role in the anti-inflammatory activity of TGAP. Overall, TGAP is a promising natural anti-inflammatory agent, with potential therapeutic applications in inflammatory disorders.
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