医学
止痛药
围手术期
叙述性评论
观察研究
癌症手术
外科
癌症
临床试验
普通外科
重症监护医学
麻醉
内科学
作者
Orlagh Murphy,Patrice Forget,Ding Ma,Donal J. Buggy
标识
DOI:10.1016/j.bja.2023.07.027
摘要
Cancer is a growing global burden; there were an estimated 18 million new cancer diagnoses worldwide in 2020. Excisional surgery remains one of the main treatments for solid organ tumours in cancer patients and is potentially curative. Cancer- and surgery-induced inflammatory processes can facilitate residual tumour cell survival, growth, and subsequent recurrence. However, it has been hypothesised that anaesthetic and analgesic techniques during surgery might influence the risk of cancer recurrence. This narrative review aims to provide an updated summary of recent observational studies and new randomised controlled clinical trials on whether certain specific anaesthetic and analgesic techniques or perioperative interventions during tumour resection surgery of curative intent materially affect long-term oncologic outcomes.
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