血清素
萧条(经济学)
神经科学
内科学
受体
心理学
5-羟色胺受体
内分泌学
心情
医学
精神科
经济
宏观经济学
出处
期刊:Jefferson Journal of Psychiatry
[Thomas Jefferson University]
日期:1994-01-01
卷期号:12 (1)
被引量:5
标识
DOI:10.29046/jjp.012.1.001
摘要
In its simplest form, the serotonin deficiency theory of depression postulates that there is a net reduction in serotonin transmission in depressive illness. The pathophysiological change may result from two different mechanisms. The first involves a decrease in serotonin (5-HT) availability which has the consequential effect of compensatory receptor up-regulation or super sensitivity. The second mechanism implies a primary defect in receptor activity and/or signal transduction. The objective of this review is to analyze the serotonin system in depression as it relates to the above two postulates.
科研通智能强力驱动
Strongly Powered by AbleSci AI