核苷
拉米夫定
核苷类似物
吉西他滨
化学
药品
药物输送
组合化学
纳米技术
药理学
材料科学
立体化学
有机化学
病毒
生物
医学
病毒学
外科
化疗
乙型肝炎病毒
作者
Kathryn J. Skilling,Michael J. Stocks,Barrie Kellam,Marianne Ashford,Tracey D. Bradshaw,Laurence Burroughs,Maria Marlow
出处
期刊:ChemMedChem
[Wiley]
日期:2018-03-23
卷期号:13 (11): 1098-1101
被引量:6
标识
DOI:10.1002/cmdc.201800063
摘要
Abstract We have synthesized a range of gelators based on the nucleoside analogues gemcitabine and lamivudine, characterizing representative gels from the series using rheology and transmission electron microscopy. Growth inhibition studies of gemcitabine derivatives confirmed the feasibility of these compounds as novel treatments, indicating the potential of nucleoside‐based gelators for localized drug delivery.
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