Nickel-Catalyzed Tandem Ueno–Stork Cyclization: Stereoselective 1,2-Dicarbofunctionalization of Cyclic Alkenes

A nickel-catalyzed tandem Ueno-Stork cyclization is developed to enable stereoselective 1,2-dicarbofunctionalization of cyclic alkenes and efficiently build various bicyclic products. This new protocol does not involve any toxic or difficult-to-remove tin reagent and is scalable and amenable to build all-carbon quaternary centers.