Supplementary Figures 1 through 6 from Anetumab Ravtansine: A Novel Mesothelin-Targeting Antibody–Drug Conjugate Cures Tumors with Heterogeneous Target Expression Favored by Bystander Effect

<p>PDF - 3895K, Supplementary Figure S1. Immunohistochemical detection of mesothelin expression in FFPE tissues of human primary ovarian cancer, pancreatic cancer, and mesothelioma. Supplementary Figure S2. Immunohistochemical detection of mouse mesothelin on Cryo embedded peritoneum sections. Supplementary Figure S3. Immunohistochemical detection of rat mesothelin on Cryo embedded tissue sections. Supplementary Figure S4. Immunohistochemical detection of cynomolgus monkey mesothelin on Cryo embedded tissue sections Supplementary Figure S5. Confirmation of mesothelin expression by IHC in vector or mesothelin-transfected tumor cell lines. Supplementary Figure S6. Anti-tumor activity of BAY 94-9343 in vivo.</p>