Covalent Organic Framework-Involved Sensors for Efficient Enrichment and Monitoring of Food Hazards: A Systematic Review

The food safety issues caused by environmental pollution have posed great risks to human health that cannot be ignored. Hence, the precise monitoring of hazard factors in food has emerged as a critical concern for the food safety sector. As a novel porous material, covalent organic frameworks (COFs) have garnered significant attention due to their large specific surface area, excellent thermal and chemical stability, modifiability, and abundant recognition sites. This makes it a potential solution for food safety issues. In this research, the synthesis and regulation strategies of COFs were reviewed. The roles of COFs in enriching and detecting food hazards were discussed comprehensively and extensively. Taking representative hazard factors in food as the research object, the expression forms and participation approaches of COFs were explored, along with the effectiveness of corresponding detection methods. Finally, the development directions of COFs in the future as well as the problems existing in practical applications were discussed, which was beneficial to promote the application of COFs in food safety and beyond.