One Size Does Not Fit All: Women Experience More Pain Than Men After Total Knee Arthroplasty

Multimodal pain regimens are universally applied to all patients, despite known differences in pain and responses to medication between patients of different sexes, ethnicities, and races. The purpose of this study was to understand the influence of patient sex on postoperative total knee arthroplasty (TKA) pain perception as well as the efficacy of perioperative pregabalin for pain control.