Colonic Amyloidosis Concomitant with Systemic Lupus Erythematosus

A 43-year-old woman with a 20-year history of systemic lupus erythematosus (SLE) complained of lower abdominal pain and a high fever.We and her previous physicians had controlled the disease activity of SLE well using predniso-lone, tacrolimus, hydroxychloroquine and mycophenolate mofetil for a number of years.Abdominal ultrasonography and computed tomography (CT) showed swelling of the ascending colonic wall (Picture 1, 2).Colonoscopy showed mucosal swelling and small red spots in the ascending colon (Picture 3).Congo red staining using the biopsy specimens