Starting From one perspective of the corporate social responsibilities(CSR)-the product safety,and its influence on the consumers,applying the basic idea of game theory,the essay studies on the model for profit distributive of manufacturer-retailer supply chain alliance,and the strategy for supply chain' fulfillment of safety responsibilities.The results show that firms can determine wholesale price through selecting β,thereby realize profit allocation;the key is to optimize the pareto for supply chain's up-stream firms and middle-stream retailers as well as down-stream consumers is signaling up-stream g firms' fulfillment of safety responsibilities through g manufacturer-retailer alliance to the consumers,and the influence on the consumer's preferences by making the products differentiate on safety responsibilities.