Efficacy and Safety of Total Glucosides of Paeony Combined with Loratadine in the Treatment of Chronic Urticaria

Objective To elucidate the efficacy and safety in the treatment of chronic urticaria with total glucosides of paeony (TGP).Methods Patients were divided into experimental group and control group in a non-randomized, open-label clinical trial.Both groups were observed at 2, 4, 8 weeks and record the efficacy.Results The efficiency of 2, 4, 8-week experimental group were higher than that of control group.Especially in 8-week.The difference between the experimental and control groups is statistically significant (P0.05).Conclusion TGP combined with Loratadine is more effective in treatment of chronic urticaria compared to loratadine alone.The longer the treatment, the better the efficacy.