Evaluation on safety risks of statin drugs

Statins are the most widely prescribed drug available pharmacotherapy for the management of high blood cholesterol levels virtually since their development. All of statin-drugs,such as atorvastatin,fluvastatin,lovastatin,pitavastatin,pravastatin,rosuvastatin and simvastatin used for prevention of cardiovascular disease event. As all know,some of the patients taking statins experience adverse effects during therapy. Such as liver toxicity,muscle injury and increased cancer risk are the top adverse effects. Therefore,it is important to understand the risks involved with the drug class and individual statins. This paper analyzes and understands the risks on safety,adverse effects and toxicity of statins from published the clinical research data in the literatures. And it also introduced to evaluate information of use and risks of statins and the 2013 Guidelines on Statins Drop Cholesterol Targets based on a four-year review of the evidence formulated by the American Heart Association and the American College of Cardiology.