核磁共振
自旋晶格弛豫
自旋回波
放松(心理学)
病理
磁共振成像
化学
自旋-自旋弛豫
医学
放射科
内科学
物理
核四极共振
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:1971-03-19
卷期号:171 (3976): 1151-1153
被引量:1244
标识
DOI:10.1126/science.171.3976.1151
摘要
Spin echo nuclear magnetic resonance measurements may be used as a method for discriminating between malignant tumors and normal tissue. Measurements of spin-lattice (T(1)) and spin-spin (T(2)) magnetic relaxation times were made in six normal tissues in the rat (muscle, kidney, stomach, intestine, brain, and liver) and in two malignant solid tumors, Walker sarcoma and Novikoff hepatoma. Relaxation times for the two malignant tumors were distinctly outside the range of values for the normal tissues studied, an indication that the malignant tissues were characterized by an increase in the motional freedom of tissue water molecules. The possibility of using magnetic relaxation methods for rapid discrimination between benign and malignant surgical specimens has also been considered. Spin-lattice relaxation times for two benign fibroadenomas were distinct from those for both malignant tissues and were the same as those of muscle.
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