OverviewScreeningFactor Influence StudiesStatistical and Mathematical ToolsResponse Surface MethodologyOptimizationVariability and QualityExchange AlgorithmsMixturesMixtures in a Constrained Region of InterestAppendix I. A Summary of Matrix AlgebraAppendix II. Experimental Designs and Models for ScreeningAppendix III. Designs for Response Surface ModelingAppendix IV. Choice of Computer SoftwareAppendix V. Symbols