沙眼衣原体
男性不育
前列腺炎
衣原体
免疫学
氧化应激
淋病奈瑟菌
不育
生殖支原体
炎症
医学
盆腔炎
尿道炎
生物
内科学
前列腺
妇科
微生物学
怀孕
癌症
遗传学
作者
Ashok Agarwal,Mohit Rana,Emily Qiu,Hashem Albunni,Albert Bui,Ralf Henkel
出处
期刊:Andrologia
[Wiley]
日期:2018-12-01
卷期号:50 (11): e13126-e13126
被引量:206
摘要
Oxidative stress (OS), defined as an overabundance of reactive oxygen species (ROS) or a deficiency of antioxidants, has been linked to sperm damage and male infertility. There are many sources of OS and inflammation including varicocele, tobacco usage, alcohol, obesity/metabolic syndrome, leukocytospermia, sexually transmitted disease (i.e., Neisseria gonorrhoeae, Chlamydia trachomatis, Treponema pallidum), bacterial prostatitis, microorganism mutations leading to more OS, and viral infections (i.e., human immunodeficiency virus, hepatitis). This review is focusing on infection and inflammation-mediated OS, the inflammatory markers underlying pathology, clinical significance in male infertility, and a brief description of the recommended treatment modalities.
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