The Gut Microbiome‐Skin Axis

We are in the midst of a revolution of knowledge regarding the human microbiome. The revolution comes from the explosion of knowledge on the role of our microbiomes in systemic disease, overall well-being, behavior, and many other health states that we previously would have never thought of microbiomes driving these complex states. Of all the complex microbiomes across the body, substantial evidence has shown that the gut microbiome appears to be the pivotal microbiome in the body. While there was always some sense of interactions between the microbiomes of the body, only recently has evidence built a fascinating picture of two- and three-way interactions between our microbiomes and organ systems. Now we are obtaining exciting data showing how one microbiome—the gut microbiome—has a definitive effect on the composition and metabolic activity of the skin microbiome. We are in a new era of discovery on how important our microbiomes are to our health and vitality. As we move into a new decade, more interactions and levels of regulation are sure to be discovered.