Iron ions-releasing mesoporous bioactive glass ultrasmall nanoparticles designed as ferroptosis-based bone cancer nanotherapeutics: Ultrasonic-coupled sol–gel synthesis, properties and iron ions release

Abstract Here, Fe ions-releasing mesoporous bioactive glass ultrasmall nanoparticles (Fe-BGn) were prepared by a facile one-pot ultrasonic-coupled sol–gel synthesis designed for use as ferroptosis-based bone cancer nanotherapeutics. The addition of 10% Fe2O3 to 85% SiO2 – 15% CaO by weight significantly reduced the particle size from about 65 nm to