中性粒细胞胞外陷阱
琥珀酸
细胞外
髓过氧化物酶
受体拮抗剂
下调和上调
医学
敌手
受体
炎症
流式细胞术
免疫学
内分泌学
药理学
内科学
生物化学
化学
基因
作者
Hongxi Li,Handan Tan,Zhangluxi Liu,Su Pan,Shiyao Tan,Yunyun Zhu,Qingfeng Wang,Guannan Su,Chunjiang Zhou,Qingfeng Cao,Peizeng Yang
标识
DOI:10.1136/bjophthalmol-2021-320880
摘要
Succinic acid could worsen EAU induced by IRBP in mice. This effect was possibly mediated by its upregulation on NETs generation and frequencies of Th1/Th17 cells in affiliation with increased production of IFN-γ/IL-17A through succinic acid-SUCNR1 axis.
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