医学
心房颤动
心脏病学
心脏淀粉样变性
内科学
疾病
入射(几何)
心源性猝死
淀粉样变性
植入式心律转复除颤器
血栓形成
心脏传导系统
心脏病
心电图
物理
光学
作者
Ala Assaf,Mario Mekhael,Charbel Noujaim,Nour Chouman,Hadi Younes,Omar Kreidieh,Nassir F. Marrouche,Eoin Donnellan
标识
DOI:10.1016/j.tcm.2023.02.004
摘要
Cardiac amyloidosis (CA) has diverse and deleterious effects on the conductive system. Atrial fibrillation is by far the most common electrophysiological manifestation of CA and is associated with more mortality, morbidity, and hospitalizations. While AF increases the risk of thrombosis regardless of the CHA2DS2-VASc score, the risk of thromboembolism seems to be high even in CA patients without AF. AV Nodal disease is prevalent and may precede the diagnosis of CA. The incidence of ventricular arrhythmias remains disputed, and the role of implantable cardioverter defibrillator devices in CA patients is controversial. Newer therapies targeted against specific types of CA have been developed, but their effects on conductive system disease are not well studied.
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