An Unusual Case of Rectal Bleeding and Abdominal Pain in a Young Man

Question: A 33-year-old white, non-Hispanic male presented to the hospital with 3 weeks of progressive abdominal pain, rectal bleeding, and constipation. His past medical history was significant for an episode of superior mesenteric vein thrombosis and small-bowel resection due to necrotic bowel 1 year ago due to unclear etiology despite a work-up including JAK2 mutation panel, antineutrophil cytoplasmic antibodies vasculitis panel, protein C, protein S, anti-thrombin 3, activated protein C resistance, lupus anticoagulant profile, along with immunoglobulin G and immunoglobulin M antiphospholipid antibodies and beta 2 glycoprotein antibodies, chronic hepatitis profile, and QuantiFERON, which were nonrevealing.