脂肪酶
抗癫痫药
千克
胰脂肪酶
比例(比率)
癫痫
化学
医学
内科学
生物化学
体重
酶
物理
精神科
量子力学
作者
Zhen Wang,Chun-Long Ke,Junfeng Liu
出处
期刊:Reaction Chemistry and Engineering
[The Royal Society of Chemistry]
日期:2023-01-01
卷期号:8 (2): 311-315
被引量:1
摘要
Economic kilogram-scale synthesis of the novel antiepileptic drug brivaracetam involving an enzymatic hydrolysis by porcine pancreatic lipase was developed in nine steps starting from commercially available dimethyl 2-propylmalonate.
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