A novel BaEVRless-LV packaging system for the production of lentiviral vectors for clinical-grade CAR-NK cell manufacturing

Chimeric antigen receptor natural killer (CAR-NK) cell therapy is an alternative immunotherapy that provides robust tumor-eliminating effects without inducing life-threatening toxicities and graft-versus-host disease. CAR-NK cell therapy has enabled the development of "off-the-shelf" products