6 patients with breast cancer were treated for 4 weeks with the antiestrogen Tamoxifen, and for another 4 weeks with a combination of Tamoxifen and levodopa. Blood samples were examined every four days during the whole period of treatment to determine secretion of prolactin. Levels of serum prolactin was not sensibly modified during treatment with Tamoxifen, while there was a significant decrease in prolactinemia during treatment with Tamoxifen and levodopa. The small number of cases observed does not allow a sufficient evaluation of the clinical effectiveness of the treatment.