医学
全身循环
桥(图论)
多样性(控制论)
离体
医学物理学
体内
重症监护医学
计算机科学
外科
内科学
生物技术
生物
人工智能
作者
Emmanouil Agrafiotis,Daniel Zimpfer,Heinrich Mächler,Gerhard Holzapfel
标识
DOI:10.1177/15266028241235876
摘要
On needs-based ex vivo monitoring of implantable devices or tissues/organs in cardiovascular simulators provides new insights and paves new paths for device prototypes. The insights gained could not only support the needs of patients, but also inform engineers, scientists and clinicians about undiscovered aspects of diseases (during routine monitoring). We analyze seminal and current work and highlight a variety of opportunities for developing preclinical tools that would improve strategies for future implantable devices. Holistically, mock circulation loop studies can bridge the gap between in vivo and in vitro approaches, as well as clinical and laboratory settings, in a mutually beneficial manner.
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