卡斯波芬金
随机化
医学
棘白菌素
随机对照试验
不利影响
置信区间
内科学
临床终点
多中心试验
外科
多中心研究
抗真菌
氟康唑
皮肤病科
作者
Álex Soriano,Patrick M. Honorè,Oliver A. Cornely,Methee Chayakulkeeree,Matteo Bassetti,Huang Haihui,Hervé Dupont,Young Keun Kim,Marin H. Kollef,Bart Jan Kullberg,Nick Manamley,Peter Pappas,John Pullman,Taylor Sandison,Cecilia Dignani,José A. Vázquez,George R. Thompson
摘要
Rezafungin, a novel, once-weekly echinocandin for the treatment of candidemia and/or invasive candidiasis (IC) was noninferior to caspofungin for day 30 all-cause mortality (ACM) and day 14 global cure in the phase 3 ReSTORE trial (NCT03667690). We conducted preplanned subgroup analyses for patients with a positive culture close to randomization in ReSTORE.
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