T2-Weighted Image Radiomics Nomogram to Predict Pancreatic Serous and Mucinous Cystic Neoplasms

With the advent of cross-sectional imaging, incidental pancreatic cystic neoplasms have become increasingly detectable. Serous cystic neoplasms (SCNs) and mucinous cystic neoplasms (MCNs) are two common types of pancreatic cystic neoplasms ( 1 van Huijgevoort NCM Del Chiaro M Wolfgang CL et al. Diagnosis and management of pancreatic cystic neoplasms: current evidence and guidelines. Nat Rev Gastroenterol Hepatol. 2019; 16: 676-689 Crossref PubMed Scopus (147) Google Scholar ). SCN is a benign neoplasm that does not require surgical treatment unless symptoms related to the compression of adjacent organs are present ( 2 European study group on cystic tumors of the P. European evidence-based guidelines on pancreatic cystic neoplasms. Gut. 2018; 67: 789-804https://doi.org/10.1136/gutjnl-2018-316027 Crossref PubMed Scopus (758) Google Scholar ). MCN is a precancerous lesion; therefore, surgical resection is generally recommended ( 2 European study group on cystic tumors of the P. European evidence-based guidelines on pancreatic cystic neoplasms. Gut. 2018; 67: 789-804https://doi.org/10.1136/gutjnl-2018-316027 Crossref PubMed Scopus (758) Google Scholar , 3 Tanaka M Fernandez-Del Castillo C Kamisawa T Jang JY Levy P Ohtsuka T Salvia R Shimizu Y Tada M Wolfgang CL Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas. Pancreatology. 2017; 17: 738-753 Crossref PubMed Scopus (1069) Google Scholar ). Using conventional imaging parameters, it is difficult to differentiate SCN from MCN, especially when both are unilocular ( 4 Mamone G Barresi L Tropea A et al. MRI of mucinous pancreatic cystic lesions: a new updated morphological approach for the differential diagnosis. Updates Surg. 2020; 72: 617-637 Crossref PubMed Scopus (6) Google Scholar ).