Synthesis of 2D VO2 Nanosheets for the Dual Optical Sensor Method by Colorimetric and Fluorometric Sensing of Catecholamines

nanosheets. This sensor showed dual-function sensing toward EP by a dominant color change and fluorescence quenching. It is capable of individually detecting and quantifying both EP and DA with high selectivity and sensitivity by using both colorimetry and fluorometry simultaneously, with the detection limits of 1.07 and 5.54 μM for colorimetric analysis, respectively, and 48.07 and 3.98 μM for fluorescence analysis, respectively. The DOSM sensor was directly applied to real urine samples and gained satisfactory recovery above 90% by means of spiked concentrations. This study has opened a new platform using the DOSM and the vanadium oxidation spectrum in a much more effective way for biosensing. The fluorescence capabilities of this metal oxide can be further applied to many sensor applications based on both fluorescence and colorimetric detection.