Role of natural active pharmaceuticals in the treatment of oral diseases

Oral diseases include periodontal and oral tumors. Current treatment methods rely largely on surgical interventions and mechanical cleaning, with a lack of targeted pharmacological therapies. Regardless, natural active compounds have now become a new focus of research for the treatment of oral diseases owing to their low toxicity, favorable biocompatibility, and multi-target effects. This review summarizes the research progress regarding the role and application potential of natural active compounds, such as berberine and curcumin, in the prevention and treatment of oral diseases.