Development of a Ratiometric Luminescence Sensor for Convenient Identifying of 1-Hydroxypyrene in Fresh Urine Depended on a CD-Centered MOF

In this work, a 3D framework, [(CH3)2NH2]+[H3O]+[Cd3(mtptc)2]·3DMF·H2O, named Cd-MOF, has been fabricated through the introduction of a symmetric and rigid multicarboxylic organic linker, 5′-methyl-[1,1′:3′,1″-triphenyl]-3,3″,5,5″-tetracarboxylic acid (H4mtptc). Results of research on luminescence sensing competence unmask that Cd-MOF is verified to be competent for a convincing ratiometric luminescence sensor for the effective identification of 1-HP (1-hydroxypyrene) among other coexisting components in both DMF/H2O solutions (DMF: N,N-dimethylformamide) and human urine by monitoring the luminescence intensity of Cd-MOF, yielding quenching constants of 6.55 × 105 M−1 in DMF/H2O solutions and 2.32 × 105 M−1 in human urine, respectively. This research provides an efficient platform for ratiometric luminescence detection of 1-HP in actual urinary environments, effectively reducing the influence of external factors on detection sensitivity. Furthermore, Cd-MOF is also proven to possess outstanding recognition performance for Trp (Tryptophan), decorated with attractive quenching constant and low LOD in both DMF/H2O system (Ksv: 2.22 × 104 M−1; LOD: 0.92 μM) and actual urine conditions (Ksv: 3.75 × 104 M−1; LOD: 0.71 μM). As a consequence, Cd-MOF is qualified to act as a dual-functional luminescence sensor for sensitively identifying 1-HP and Trp as expected.