NHC/Photoredox Dual Catalysis Directs N-methyl Radical Coupling for Decarboxylative Synthesis of α-N-Aryl amino Ketones

Synergistic NHC/photoredox catalysis enables α- N -aryl amino ketone synthesis via stabilized N -methyl radicals, preventing dimerization. Base-mediated radical generation and acyl azolium-guided coupling ensure broad scope under mild conditions.